姓名:喻青松 职称:副教授 邮箱:yuqs at mail.buct.edu.cn 办公地址:化纤楼104 个人金沙检测线路js69主页:https://faculty.buct.edu.cn/life/yqs/main.htm |
教育背景:
2004.9-2008.6 北京化工大学材料学院,工学学士(生物功能材料专业)
2008.9-2014.6 中国科学院化学研究所,理学博士(高分子化学与物理专业)
工作经历:
2014.7-2017.6 北京化工大学生命学院,博士后
2017.7-至今 北京化工大学生命学院,副教授
学术**:
《biomaterials》、《acs applied materials & interfaces》、《theranostics》等多本学术期刊审稿人,国家自然科学基金函评专家,教育部学位论文评审专家。
主要研究领域:
1. 纳米药物纳米特性与递送过程生理屏障相关性;
2. 新型高效抗肿瘤纳米药物研发;
3. 同步放化疗、声动力治疗以及免疫治疗;
4. 纳米药物规模化制备及临床转化。
获奖及荣誉:
2019年 北京化工大学青年英才“百人计划”
科研项目:
2016年 国家自然科学基金青年项目
2018年 国家自然科学基金面上项目
2018年 教育部zbyy联合基金
2020年 国家自然科学基金面上项目
代表性著作:
1. yu, y.; xiang, k.; xu, m.; li, y.; cui, j.; zhang, l.; tang, x.; zhu, x.; qian, l.; zhang, m.; yang, y.; yu, q.*; shen, y.; gan, z., prodrug nanomedicine inhibits chemotherapy-induced proliferative burst by altering the deleterious intercellular communication. acs nano2021, 15 (1), 781-796.
2. shi, r.; zhang, j.; niu, k.; li, w.; jiang, n.; li, j.; yu, q.*; wu, c.*, electrospun artificial periosteum loaded with dfo contributes to osteogenesis via the tgf-β1/smad2 pathway. biomaterials science2021, 9, 2090-2102.
3. xu, x.; liu, k.; jiao, b.; luo, k.; ren, j.; zhang, g.*; yu, q.*; gan, z*., mucoadhesive nanoparticles based on ros activated gambogic acid prodrug for safe and efficient intravesical instillation chemotherapy of bladder cancer. journal of controlled release2020, 324, 493-504.
4. qin, m.; cao, z.; wen, j.; yu, q.; liu, c.; wang, f.; zhang, j.; yang, f.; li, y.; fishbein, g.; yan, s.; xu, b.; hou, y.; ning, z.; nie, k.; jiang, n.; liu, z.; wu, j.; yu, y.; li, h.; zheng, h.; li, j.; jin, w.; pang, s.; wang, s.; chen, j.*; gan, z.*; he, z.*; lu, y.*, an antioxidant enzyme therapeutic for covid-19. advanced materials2020, 32 (43).
5. luo, k.; guo, w.; yu, y.; xu, s.; zhou, m.; xiang, k.; niu, k.; zhu, x.; zhu, g.; an, z.; yu, q.*; gan, z.*, reduction-sensitive platinum (iv)-prodrug nano-sensitizer with an ultra-high drug loading for efficient chemo-radiotherapy of pt-resistant cervical cancer in vivo. journal of controlled release2020, 326, 25-37.
6. guo, d.; li, l.; zhu, x.; heeney, m.; li, j.; dong, l.; yu, q.; gan, z.; gu, x.*; tan, l.*, naphthalene diimide based near-infrared luminogens with aggregation-induced emission characteristics for biological imaging and high mobility ambipolar transistors. science china-chemistry2020, 63 (9), 1198-1207.
7. zhou, q.; shao, s.; wang, j.; xu, c.; xiang, j.; piao, y.; zhou, z.; yu, q.; tang, j.; liu, x.; gan, z.; mo, r.; gu, z.; shen, y., enzyme-activatable polymer-drug conjugate augments tumour penetration and treatment efficacy. nature nanotechnology2019, 14 (8), 799- .
8. zhang, y.; fang, q.; niu, k.; gan, z.; yu, q.*; gu, t.*, time-dependently slow-released multiple-drug eluting external sheath for efficient long-term inhibition of saphenous vein graft failure. journal of controlled release2019, 293, 172-182.
9. zhou, d.-h.; zhang, g.; yu, q.-s.*; gan, z.-h.*, folic acid modified polymeric micelles for intravesical instilled chemotherapy. chinese journal of polymer science2018, 36 (4), 479-487.
10. zhang, x.; he, f.; xiang, k.; zhang, j.; xu, m.; long, p.; su, h.; gan, z.*; yu, q.*, cd44-targeted facile enzymatic activatable chitosan nanoparticles for efficient antitumor therapy and reversal of multidrug resistance. biomacromolecules 2018, 19 (3), 883-895.
11. zhang, j.; tang, h.; shen, y.; yu, q.*; gan, z.*, shell-sheddable poly(n-2-hydroxypropyl methacrylamide) polymeric micelles for dual-sensitive release of doxorubicin. macromolecular rapid communications2018, 39 (20).
12. tang, h.; zhang, j.; tang, j.; shen, y.; guo, w.; zhou, m.; wang, r.; jiang, n.; gan, z.*; yu, q.*, tumor specific and renal excretable star-like triblock polymer-doxorubicin conjugates for safe and efficient anticancer therapy. biomacromolecules2018, 19 (7), 2849-2862.
13. tang, h.; tang, j.; shen, y.; guo, w.-x.; zhou, m.; wang, r.-h.; jiang, n.; gan, z.-h.*; yu, q.-s.*, comb-like poly(n-(2-hydroxypropyl) methacrylamide) doxorubicin conjugates: the influence of polymer architecture and composition on the biological properties. chinese journal of polymer science2018, 36 (11), 1225-1238.
14. yan, x.; yu, q.*; guo, l.; guo, w.; guan, s.; tang, h.; lin, s.; gan, z.*, positively charged combinatory drug delivery systems against multi-drug-resistant breast cancer: beyond the drug combination. acs applied materials & interfaces2017, 9 (8), 6804-6815.
15. shen, t.; xu, x.; guo, l.; tang, h.; diao, t.; gan, z.; zhang, g.*; yu, q.*, efficient tumor accumulation, penetration and tumor growth inhibition achieved by polymer therapeutics: the effect of polymer architectures. biomacromolecules2017, 18 (1), 217-230.
16. shen, t.; guan, s.; gan, z.; zhang, g.*; yu, q.*, polymeric micelles with uniform surface properties and tunable size and charge: positive charges improve tumor accumulation. biomacromolecules2016, 17 (5), 1801-1810.
17. du, n.; guo, w.; yu, q.*; guan, s.; guo, l.; shen, t.; tang, h.; gan, z.*, poly(d,l-lactic acid)-block-poly(n-(2-hydroxypropyl) methacrylamide) nanoparticles for overcoming accelerated blood clearance and achieving efficient anti-tumor therapy. polymer chemistry2016, 7 (36), 5719-5729.
18. yu, q.; zhang, j.; zhang, g.; gan, z., synthesis and functions of well-defined polymer-drug conjugates as efficient nanocarriers for intravesical chemotherapy of bladder cancer(a). macromolecular bioscience2015, 15 (4), 509-520.
19. yu, q.#; wei, z.#; shi, j.; guan, s.; du, n.; shen, t.; tang, h.; jia, b.; wang, f.; gan, z., polymer-doxorubicin conjugate micelles based on poly(ethylene glycol) and poly(n-(2-hydroxypropyl) methacrylamide): effect of negative charge and molecular weight on biodistribution and blood clearance. biomacromolecules 2015, 16 (9), 2645-2655.
20. yu, q.#; dong, c.#; zhang, j.; shi, j.; jia, b.; wang, f.; gan, z., synthesis of poly(ethylene glycol)-b-poly(n-(2-hydroxypropyl) methacrylamide) block copolymers with well-defined structures and their influence on in vivo circulation and biodistribution. polymer chemistry2014, 5 (19), 5617-5627.
21. wei, z.; yu, q.; gan, z., thermosensitive block copolymers peg-b-pbemagg containing functional pendant amino groups. macromolecular research2012, 20 (3), 313-318.
教师寄语:
希望肿瘤能被我们这一代人攻克,加入金沙检测线路js69与我们一起改变人类的未来。
招生要求:
专业不限,但是要刻苦、刻苦、刻苦!